Posterior scleral application of a mitomycin C-soaked sponge during trabeculectomy

AIM: To evaluate the safety and efficacy of posterior scleral application (a modified technique) an antimetabolite mitomycin C-soaked sponge in trabeculectomy for patients with glaucoma. METHODS: This retrospective study included 101 (115 eyes) glaucoma (aged 12–83y) who underwent using a placement method. A piece 3.5×10 mm2 was placed vertically posteriorly long side perpendicular to limbus. The C concentration exposure time were 0.2–0.5 mg/mL 1–5min, respectively. Intraocular pressure, best-corrected visual acuity, hypotensive medications recorded at baseline final visit. Complications, interventions required, bleb morphology postoperatively. primary outcome safety, including complications morphology; secondary success rate. RESULTS: At follow-up [median 28mo, range 7–67mo interquartile (IQR) 13mo], qualified (cumulative) rate 93.0% complete 60.0%. No bleb-related observed. mean height, extent, vascularity grades 0.6±0.9, 1.1±0.4, 2.4±0.9, All Seidel tests negative. posteriority grade 0.8±0.4. CONCLUSION: Trabeculectomy corneal limbus is safe effective.